INDICATIONS : HALOTHANE
Your Ultimate Resource for Anesthesia Meds!
What is Anesthesia? An anesthetic (anaesthetic), is a drug that causes anesthesia — reversible loss of sensation. They contrast with analgesics (painkillers), which relieve pain without eliminating sensation. These drugs are generally administered to facilitate surgery. A wide variety of drugs are used in modern anesthetic practice. Many are rarely used outside of anesthesia, although others are used commonly by all disciplines. Anesthetics are categorized in to two classes: general anesthetics, which cause a reversible loss of consciousness, and local anesthetics, which cause a reversible loss of sensation for a limited region of the body while maintaining consciousness. Combinations of anesthetics are sometimes used for their synergistic and additive therapeutic effects, however, adverse effects may also be increased.
More on Halothane Below
Halothane vapour (trademarked as Fluothane) is an inhalational general anaesthetic. Its IUPAC name is 2-bromo-2-chloro-1,1,1-trifluoroethane. It is the only inhalational anaesthetic agent containing a bromine atom; there are several other halogenated anesthesia agents which lack the bromine atom and do contain the fluorine and chlorine atoms present in halothane.
It is colourless and pleasant-smelling, but unstable in light. It is packaged in dark-coloured bottles and contains 0.01% thymol as a stabilising agent. Halothane is a core medicine in the World Health Organization's "Essential Drugs List", which is a list of minimum medical needs for a basic health care system. Its use in developed countries however has almost entirely been superseded by newer inhalational anaesthetic agents.
Related substances: Chemically, halothane is not an ether; it is an alkane. The structure has one stereocentre, so there are (R) and (S) optical isomers. Attempts to find anaesthetics with less metabolism led to halogenated ethers such as enflurane and isoflurane. The incidence of hepatic reactions with these agents is lower. The exact degree of hepatotoxic potential of enflurane is debated, although it is minimally metabolised. Isoflurane is essentially not metabolised and reports of associated liver injury are quite rare. Small amounts of trifluoroacetic acid can be formed from both halothane and isoflurane metabolism and possibly accounts for cross sensitisation of patients between these agents.
AnestaWeb ::: Real People. Real Information.
Owned and Operated by AnestaWeb, Inc.
AnestaWeb ::: Disclaimer
The contents of the AnesthesiaMedications.com or Anesthesiameds.com Website, such as text, graphics, images, and other material contained on the AnesthesiaMedications.com or AnesthesiaMeds.com Website ("Content") are for informational purposes only. This site provides only general information about medication. It does not cover all possible uses, actions, precautions, side effects, or interactions of the medicines mentioned. The information not intended as medical advice for individual problems or for making an evaluation as to the risks and benefits of taking a particular medication. The treating physician, relying on experience and knowledge of the patient, must determine dosages and the best treatment for the patient. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. AnestaWeb does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the Site. Reliance on any information provided by AnestaWeb, AnestaWeb employees, others appearing on the Site at the invitation of AnestaWeb, or other visitors to the Site is solely at your own risk.
Real People. Real Information.®