INDICATIONS : MIDAZOLAM
Your Ultimate Resource for Anesthesia Meds!
More on Midazolam Below
Midazolam (Dormicum, Hypnovel and Versed) is a short-acting drug in the benzodiazepine class that is used for treatment of acute seizures and for inducing sedation and amnesia before medical procedures. It has potent anxiolytic, amnestic, hypnotic, anticonvulsant, skeletal muscle relaxant, and sedative properties. Midazolam has a fast recovery time and is the most commonly used benzodiazepine as a premedication for sedation; less commonly it is used for induction and maintenance of anesthesia. Flumazenil is a benzodiazepine antagonist drug that can be used to treat an overdose of midazolam as well as to reverse sedation. However, flumazenil can trigger seizures in mixed overdoses and in benzodiazepine dependent individuals so is not used in most cases.
Contraindications and special caution: Benzodiazepines require special precaution if used in the elderly, during pregnancy, in children, alcohol or drug-dependent individuals and individuals with comorbid psychiatric disorders. Additional caution is required in critically ill patients as accumulation of midazolam and its active metabolites may occur. Kidney or liver impairments may slow down the elimination of midazolam leading to prolonged and enhanced effects. Contraindications include hypersensitivity, acute narrow angle glaucoma, shock, hypotension, head injury. Most are relative contraindications.
Side effects of midazolam include tolerance, withdrawal symptoms, confusion, amnesia including anterograde amnesia, ataxia, drowsiness, cognitive impairment, sedation and an increased risk of falls in the elderly. People experiencing amnesia as a side effect of midazolam are generally unaware that their memory is impaired.
AnestaWeb ::: Real People. Real Information.
Owned and Operated by AnestaWeb, Inc.
AnestaWeb ::: Disclaimer
The contents of the AnesthesiaMedications.com or Anesthesiameds.com Website, such as text, graphics, images, and other material contained on the AnesthesiaMedications.com or AnesthesiaMeds.com Website ("Content") are for informational purposes only. This site provides only general information about medication. It does not cover all possible uses, actions, precautions, side effects, or interactions of the medicines mentioned. The information not intended as medical advice for individual problems or for making an evaluation as to the risks and benefits of taking a particular medication. The treating physician, relying on experience and knowledge of the patient, must determine dosages and the best treatment for the patient. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. AnestaWeb does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the Site. Reliance on any information provided by AnestaWeb, AnestaWeb employees, others appearing on the Site at the invitation of AnestaWeb, or other visitors to the Site is solely at your own risk.
What is Anesthesia? An anesthetic (anaesthetic), is a drug that causes anesthesia — reversible loss of sensation. They contrast with analgesics (painkillers), which relieve pain without eliminating sensation. These drugs are generally administered to facilitate surgery. A wide variety of drugs are used in modern anesthetic practice. Many are rarely used outside of anesthesia, although others are used commonly by all disciplines. Anesthetics are categorized in to two classes: general anesthetics, which cause a reversible loss of consciousness, and local anesthetics, which cause a reversible loss of sensation for a limited region of the body while maintaining consciousness. Combinations of anesthetics are sometimes used for their synergistic and additive therapeutic effects, however, adverse effects may also be increased.
Real People. Real Information.®